Flibanserin, a kind of 5-HT receptor modulator, is used to treat premenopausal women who have developed a non-congenital form of hypoactive sexual drive problem (HSDD).
When it comes to treating premenopausal women with hypoactive sexual desire disorder (HSDD), flibanserin was one of the first drugs to get FDA clearance in August 2015. Originally developed as an antidepressant, this drug was repurposed to treat hypoactive sexual dysfunction after failing to show adequate effectiveness in many studies. Flibanserin’s method of action involves its tight affinity with 5-HTA1 and 5-HTA2 receptors, demonstrating agonist effect on 5-HTA1 and antagonist on 5-HTA2, which decreases serotonin levels in the brain while boosting the amount of dopamine and norepinephrine neurotransmitters.
Flibanserin not only binds with great affinity to serotonin receptors in the brain, but also to 5-HT1A and 5-HT2A receptors. Flibanserin, on the other hand, may occupy 5-HT2A receptors in greater numbers than 5-HT(1A) receptors under situations when there are elevated amounts of 5-HT in the brain, such as during periods of stress. Flibanserin may also have modest antagonism of D4 (dopamine) receptors, in addition to 5-HT2B and 5-HTB2C. Because of its effect on neurotransmitter receptors, it can lower serotonin levels while raising norepinephrine and dopamine, leading to a more favorable therapeutic outcome.
For at least 6 hours after taking Flibanserin, patients should not drive or partake in any activity that calls for full mental awareness. Do not combine Flibanserin with other CNS depressants including opioids, diphenhydramine, benzodiazepines, or hypnotics. The use of flibanserin alone has been linked to syncope and low blood pressure.
Numerous mouse studies have shown that there is a dose-dependent increase in the prevalence of malignant mammary tumors in female mice (exposure levels 3 and 10 times higher than the suggested clinical dose). Male mice and both male and female rats showed no sign of this impact.
Buying addyi online without a prescription and from an untrustworthy source is not recommended. Your doctor will likely have some recommendations for you, but if you want to be absolutely sure, you may do some more investigating online to locate reliable pharmacies. Additionally, you can save yourself some time and energy by purchasing Flibanserin from our pharmacy (name of pharmacy), which has been operating in the pharmaceutical market for quite some time and has a stellar reputation among its clientele and business associates.